Estradiol Online
Brand names: Estrace, Vivelle-Dot, Climara
Estradiol is a bioidentical form of estrogen used in hormone replacement therapy (HRT) for menopause symptoms. Available as tablets, patches, transdermal creams, or vaginal inserts. It's the most commonly prescribed estrogen for menopausal symptom relief.
Prices last checked · each provider's date is under its price
* Prices are based on our most recent research and may not reflect current pricing. Verify directly with the provider.
Ranked lists
How Estradiol Works
Estradiol replaces the estrogen that the ovaries stop producing during menopause. Declining estrogen causes hot flashes, night sweats, vaginal dryness, mood changes, and bone density loss. By restoring estrogen levels, estradiol alleviates these symptoms and helps protect against osteoporosis.
What to Expect
Hot flashes and night sweats typically improve within 2-4 weeks. Vaginal dryness may take 4-12 weeks to fully resolve. Mood and sleep improvements are usually noticed within the first month. Bone density benefits require long-term use.
Estradiol Pricing Comparison
Sorted by lowest starting price.
Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.
- Visit Hone HealthWomen's HRT$25–$155● Consults● Shipping● Labschecked
- Visit TelyRxEstradiol Tablets$33.99○ Consults○ Shipping○ Labschecked
- Visit AlloyEstradiol Pill$39.9925% off first order (code PILL25)● Consults● Shipping○ LabscheckedEstradiol Patch$100● Consults● Shipping○ LabscheckedEstradiol Spray/Gel (Evamist)$69.9925% off first order (code HRT25)● Consults● Shipping○ LabscheckedVaginal Estrogen Cream$39.99● Consults● Shipping○ Labschecked
- Visit Midi HealthMenopause & Perimenopause Care (HRT, non-hormonal)$50–$250Billed per visit: insurance-covered (typically ~$50 copay/coinsurance) or $250 first visit / $150 follow-up self-pay; medication billed separately through the patient's pharmacy● Consults○ Shipping○ Labschecked
- Visit AgelessRxWomen's Hormone Care$50● Consults● Shipping○ Labschecked
- Visit WinonaEstrogen Tablets (Estradiol, FDA-approved)$54An FDA-approved finished medicine, not a compounded preparation. Price is a floor, shown on the site as 'from'● Consults● Shipping○ LabscheckedEstrogen Body Cream (with Progesterone)$89Compounded by a state-licensed pharmacy; the active ingredients are FDA-approved but the finished medicine is not● Consults● Shipping○ LabscheckedEstrogen Patch (FDA-approved)$149An FDA-approved finished medicine, not a compounded preparation. Price is a floor, shown on the site as 'from'● Consults● Shipping○ LabscheckedVaginal Estrogen Cream$89Compounded by a state-licensed pharmacy; the active ingredients are FDA-approved but the finished medicine is not● Consults● Shipping○ LabscheckedEstrogen Body Cream$89Compounded by a state-licensed pharmacy; the active ingredients are FDA-approved but the finished medicine is not● Consults● Shipping○ Labschecked
- Visit EffectyEstradiol (tablet, cream or patch) + Progesterone$55–$180$100 off first multi-month order● Consults● Shipping○ Labschecked
- Visit Joi + BlokesBioidentical Hormone Therapy (BHRT)$59● Consults● Shipping○ Labschecked
- Visit HealthspanBi-Est 50/50 Cream$64● Consults● Shipping○ Labschecked
- Visit Pallas HealthWomen's HRT (estradiol topical/cream/patch, estriol cream)$66–$90Billed per 12-week supply ($199–269)● Consults● Shipping○ Labschecked
- Visit Gala HealthMenopause HRT (estradiol pill/patch, progesterone)$69● Consults● Shipping○ Labschecked
- Visit NoomNoom HRTRx (Menopause Hormone Therapy)$69–$149Cream $69 intro (then $89/mo); patch $99 intro (then $149/mo)● Consults● Shipping○ Labschecked
- Visit ProlongMDEstradiol (oral)$79○ Consults● Shipping○ Labschecked
- Peter MD52Visit Peter MDWomen's HRT$79–$139● Consults● Shipping○ Labschecked
- Visit CoreAge RxWomen's HRT (estrogen/progesterone)$80–$150● Consults● Shipping○ Labschecked
- Visit Precision TelemedWomen's HRT (estradiol / progesterone)$83–$199.99● Consults● Shipping● Labschecked
- Visit Nu Image MedicalWomen's Sexual Health (compounded gel / estradiol vaginal cream)$84● Consults● Shipping○ Labschecked
- Visit JosieEstradiol Patch or Cream (HRT)$90–$100Billed $269–$299 per 3 months● Consults● Shipping○ Labschecked
- Heally64Visit HeallyPerimenopause Treatment$99● Consults● Shipping○ Labschecked
- Visit Inner BalanceOestra Bioidentical Hormone Cream (compounded)$99.5–$199$199/mo for the first 6 months, then $99.50/mo; optional labs extra● Consults● Shipping○ Labschecked
- Visit He & She MDEstradiol (patch, gel, tablet)$125Billed $375 per 3 months● Consults● Shipping○ Labschecked
- Visit Ivim HealthWomen's Hormone Optimization$125–$199$75/mo membership + medication from $50/mo (billed separately)● Consults● Shipping○ Labschecked
- Visit Fem ExcelEstradiol (compounded)$149$50/mo medication billed every 2 months + mandatory $99/mo membership (first month free); $99 consultation + at-home test kit up front● Consults○ Shipping● Labschecked
- Visit Defy MedicalWomen's Bioidentical HRT$150–$250○ Consults● Shipping○ Labschecked
- Visit Fountain TRTWomen's Hormone Therapy (Testosterone/Estrogen/Progesterone)$150–$199● Consults● Shipping● Labschecked
- Visit Direct MedsWomen's HRT (Nuvella): estradiol, progesterone, DHEA$180–$197$540 for the first 3 months, then $180/mo● Consults● Shipping○ Labschecked
- Visit GoodLife HealthHormone Optimization (estrogen/progesterone/testosterone/thyroid)$299● Consults○ Shipping● Labschecked
- Visit Pandia HealthMenopause HRT (patch, pill, vaginal)Quoted after consult○ Consults● Shipping○ Labschecked
- Visit EvernowEstradiol (patch, pill, gel)Quoted after consult○ Consults● Shipping○ Labschecked
- Visit Elektra HealthMenopause Hormone Therapy (FDA-approved)Quoted after consult○ Consults○ Shipping○ Labschecked
- Visit Marek HealthWomen's Hormone TherapyQuoted after consult○ Consults● Shipping○ Labschecked
- Visit MyMenopauseRxBioidentical HRT (estradiol, progesterone, DHEA)Quoted after consult○ Consults○ Shipping○ Labschecked
- Visit Renew YouthRenew Woman Estrogen/Progesterone TherapyQuoted after consultFree initial phone consultation● Consults● Shipping○ Labschecked
- Visit BiltRxWomen's HRTQuoted after consult○ Consults○ Shipping○ Labschecked
- Visit BodyLogicMDBioidentical HRT for Women (compounded)Quoted after consult○ Consults○ Shipping○ Labschecked
| Provider | Score | Product | Price/mo | Includes | |
|---|---|---|---|---|---|
 Hone Health | 78 | Women's HRT | $25–$155 checked | ● Consults● Shipping● Labs | Visit |
 TelyRx | 72 | Estradiol Tablets | $33.99 checked | ○ Consults○ Shipping○ Labs | Visit |
 Alloy | 73 | Estradiol Pill | $39.99 25% off first order (code PILL25) checked | ● Consults● Shipping○ Labs | Visit |
| Estradiol Patch | $100 checked | ● Consults● Shipping○ Labs | |||
| Estradiol Spray/Gel (Evamist) | $69.99 25% off first order (code HRT25) checked | ● Consults● Shipping○ Labs | |||
| Vaginal Estrogen Cream | $39.99 checked | ● Consults● Shipping○ Labs | |||
 Midi Health | 75 | Menopause & Perimenopause Care (HRT, non-hormonal) | $50–$250 Billed per visit: insurance-covered (typically ~$50 copay/coinsurance) or $250 first visit / $150 follow-up self-pay; medication billed separately through the patient's pharmacy checked | ● Consults○ Shipping○ Labs | Visit |
 AgelessRx | 73 | Women's Hormone Care | $50 checked | ● Consults● Shipping○ Labs | Visit |
 Winona | 75 | Estrogen Tablets (Estradiol, FDA-approved) | $54 An FDA-approved finished medicine, not a compounded preparation. Price is a floor, shown on the site as 'from' checked | ● Consults● Shipping○ Labs | Visit |
| Estrogen Body Cream (with Progesterone) | $89 Compounded by a state-licensed pharmacy; the active ingredients are FDA-approved but the finished medicine is not checked | ● Consults● Shipping○ Labs | |||
| Estrogen Patch (FDA-approved) | $149 An FDA-approved finished medicine, not a compounded preparation. Price is a floor, shown on the site as 'from' checked | ● Consults● Shipping○ Labs | |||
| Vaginal Estrogen Cream | $89 Compounded by a state-licensed pharmacy; the active ingredients are FDA-approved but the finished medicine is not checked | ● Consults● Shipping○ Labs | |||
| Estrogen Body Cream | $89 Compounded by a state-licensed pharmacy; the active ingredients are FDA-approved but the finished medicine is not checked | ● Consults● Shipping○ Labs | |||
 Effecty | 67 | Estradiol (tablet, cream or patch) + Progesterone | $55–$180 $100 off first multi-month order checked | ● Consults● Shipping○ Labs | Visit |
 Joi + Blokes | 75 | Bioidentical Hormone Therapy (BHRT) | $59 checked | ● Consults● Shipping○ Labs | Visit |
 Healthspan | 71 | Bi-Est 50/50 Cream | $64 checked | ● Consults● Shipping○ Labs | Visit |
 Pallas Health | 66 | Women's HRT (estradiol topical/cream/patch, estriol cream) | $66–$90 Billed per 12-week supply ($199–269) checked | ● Consults● Shipping○ Labs | Visit |
| Gala Health | 66 | Menopause HRT (estradiol pill/patch, progesterone) | $69 checked | ● Consults● Shipping○ Labs | Visit |
 Noom | 60 | Noom HRTRx (Menopause Hormone Therapy) | $69–$149 Cream $69 intro (then $89/mo); patch $99 intro (then $149/mo) checked | ● Consults● Shipping○ Labs | Visit |
| ProlongMD | 60 | Estradiol (oral) | $79 checked | ○ Consults● Shipping○ Labs | Visit |
| Peter MD | 52 | Women's HRT | $79–$139 checked | ● Consults● Shipping○ Labs | Visit |
 CoreAge Rx | 54 | Women's HRT (estrogen/progesterone) | $80–$150 checked | ● Consults● Shipping○ Labs | Visit |
 Precision Telemed | 71 | Women's HRT (estradiol / progesterone) | $83–$199.99 checked | ● Consults● Shipping● Labs | Visit |
| Nu Image Medical | 71 | Women's Sexual Health (compounded gel / estradiol vaginal cream) | $84 checked | ● Consults● Shipping○ Labs | Visit |
 Josie | 58 | Estradiol Patch or Cream (HRT) | $90–$100 Billed $269–$299 per 3 months checked | ● Consults● Shipping○ Labs | Visit |
| Heally | 64 | Perimenopause Treatment | $99 checked | ● Consults● Shipping○ Labs | Visit |
| Inner Balance | 54 | Oestra Bioidentical Hormone Cream (compounded) | $99.5–$199 $199/mo for the first 6 months, then $99.50/mo; optional labs extra checked | ● Consults● Shipping○ Labs | Visit |
 He & She MD | 65 | Estradiol (patch, gel, tablet) | $125 Billed $375 per 3 months checked | ● Consults● Shipping○ Labs | Visit |
 Ivim Health | 58 | Women's Hormone Optimization | $125–$199 $75/mo membership + medication from $50/mo (billed separately) checked | ● Consults● Shipping○ Labs | Visit |
 Fem Excel | 64 | Estradiol (compounded) | $149 $50/mo medication billed every 2 months + mandatory $99/mo membership (first month free); $99 consultation + at-home test kit up front checked | ● Consults○ Shipping● Labs | Visit |
 Defy Medical | 72 | Women's Bioidentical HRT | $150–$250 checked | ○ Consults● Shipping○ Labs | Visit |
| Fountain TRT | 61 | Women's Hormone Therapy (Testosterone/Estrogen/Progesterone) | $150–$199 checked | ● Consults● Shipping● Labs | Visit |
 Direct Meds | 75 | Women's HRT (Nuvella): estradiol, progesterone, DHEA | $180–$197 $540 for the first 3 months, then $180/mo checked | ● Consults● Shipping○ Labs | Visit |
 GoodLife Health | 58 | Hormone Optimization (estrogen/progesterone/testosterone/thyroid) | $299 checked | ● Consults○ Shipping● Labs | Visit |
 Pandia Health | 73 | Menopause HRT (patch, pill, vaginal) | Quoted after consult checked | ○ Consults● Shipping○ Labs | Visit |
 Evernow | 68 | Estradiol (patch, pill, gel) | Quoted after consult checked | ○ Consults● Shipping○ Labs | Visit |
| Elektra Health | 63 | Menopause Hormone Therapy (FDA-approved) | Quoted after consult checked | ○ Consults○ Shipping○ Labs | Visit |
| Marek Health | 62 | Women's Hormone Therapy | Quoted after consult checked | ○ Consults● Shipping○ Labs | Visit |
| MyMenopauseRx | 61 | Bioidentical HRT (estradiol, progesterone, DHEA) | Quoted after consult checked | ○ Consults○ Shipping○ Labs | Visit |
 Renew Youth | 61 | Renew Woman Estrogen/Progesterone Therapy | Quoted after consult Free initial phone consultation checked | ● Consults● Shipping○ Labs | Visit |
 BiltRx | 60 | Women's HRT | Quoted after consult checked | ○ Consults○ Shipping○ Labs | Visit |
 BodyLogicMD | 54 | Bioidentical HRT for Women (compounded) | Quoted after consult checked | ○ Consults○ Shipping○ Labs | Visit |
Common Side Effects
- •Breast tenderness
- •Headaches
- •Nausea
- •Bloating
- •Mood changes
- •Breakthrough bleeding (early in treatment)
Serious Side Effects
- !Blood clots (risk is lower with transdermal forms)
- !Stroke
- !Breast cancer (with long-term use, especially combined with progestin)
- !Endometrial cancer (if taken without progesterone in women with a uterus)
Estradiol Is Not For
- ✗Women with a history of breast cancer
- ✗Women with active blood clots or clotting disorders
- ✗Women with unexplained vaginal bleeding
- ✗Women with severe liver disease
Estradiol — Frequently Asked Questions
What is estradiol used for?
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Estradiol is prescribed to treat menopause symptoms including hot flashes, night sweats, vaginal dryness, and mood changes. It's also used to prevent osteoporosis in postmenopausal women.
How much does estradiol cost from telehealth HRT providers?
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Estradiol from most telehealth menopause providers costs about $50-150/month depending on the delivery method. Oral tablets are cheapest, patches are mid-range, and custom compounded creams are most expensive.
Do I need to take progesterone with estradiol?
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If you have an intact uterus, yes. Taking estrogen without progesterone increases the risk of endometrial cancer. Women who have had a hysterectomy can typically take estradiol alone. Your provider will determine the right combination.
Medical disclaimer: The information on this page is for educational purposes only and is not medical advice.Estradiol requires a prescription from a licensed healthcare provider. Side effects, risks, and suitability vary by individual. Always consult your doctor before starting, stopping, or changing any medication. Telehealth Match is not a healthcare provider.
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