Defy Medical
Physician-led telemedicine hormone clinic offering TRT, women's HRT, peptides, GLP-1s, and sexual-health treatments, dispensed through three named partner pharmacies.
Our Verdict
Defy Medical scores 71.9/100 in our independent evaluation — good overall, standing out most for reputation and experience. Plans start at $150/mo.
What we like
What to watch
Full Review
Defy Medical is a physician-led telemedicine practice, in operation since 2011, specializing in testosterone replacement therapy, women's bioidentical hormone therapy, peptides, GLP-1 weight-loss medications, and sexual-dysfunction treatment. Labs are required before prescribing, and medications are dispensed through three partner pharmacies named on its pharmacy contact page: Empower Pharmacy (Houston), APS Pharmacy (Palm Harbor, FL) and Hallandale Pharmacy (Fort Lauderdale). The brand carries a strong 4.8 Trustpilot rating across more than 4,100 reviews and responds to 94% of negative reviews within a day, reflecting an unusually engaged support operation for its size. The main drawback is pricing opacity: costs aren't published on the website, and patients must pay for a roughly $250 initial consultation before learning what ongoing treatment will cost, with some also reporting fulfillment delays afterward.
Last researched: Sep 19, 2026
Pricing
Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.
| Treatment | Category | Price/mo | Includes | Notes |
|---|---|---|---|---|
| Initial Consultation | Hormone Therapy | $250 | ● Consults○ Lab work○ Shipping | No subscription needed |
| Testosterone Replacement Therapy (TRT) | Hormone Therapy | $160–$250 | ○ Consults○ Lab work● Shipping | Subscription required |
| GLP-1 Weight Loss (Semaglutide/Tirzepatide) | Weight Loss / GLP-1 | $150–$250 | ○ Consults○ Lab work● Shipping | Subscription required |
| Women's Bioidentical HRT | Hormone Therapy | $150–$250 | ○ Consults○ Lab work● Shipping | Subscription required |
Where Defy Medical medication comes from
Defy's pharmacy contact page lists three dispensing pharmacies: Empower Pharmacy (Houston), APS Pharmacy (Palm Harbor, FL) and Hallandale Pharmacy (Fort Lauderdale). Its store can be filtered by pharmacy.
Score Breakdown
How Defy Medical Stacks Up
Defy Medical — Frequently Asked Questions
Is Defy Medical legit?
▾
We rate Defy Medical's trust & safety at 72/100 (good), based on FDA compliance, licensing, and pricing transparency. Its overall score across all five of our scoring dimensions is 71.9/100 — see the full breakdown above.
How much does Defy Medical cost?
▾
Defy Medical's plans start at $150/mo. Exact pricing varies by treatment — see the pricing table above for a breakdown by product. Prices were last verified 2026-09-19.
Does Defy Medical require a subscription?
▾
It depends on the plan. Some Defy Medical treatments require an ongoing subscription and some don't — check the "Notes" column in the pricing table above.
What does Defy Medical treat?
▾
Defy Medical offers treatment in: Hormone Therapy, Weight Loss / GLP-1, Sexual Health.