RxSpan MD vs Synergy Rx: Which Is Better?
Head-to-head comparison of RxSpan MD and Synergy Rx based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.
Our Verdict
RxSpan MD scores higher overall in our independent evaluation (59.1/100 vs 51.9/100), leading on trust & safety, experience, product range, reputation. Synergy Rx comes out ahead on value. Synergy Rx has the lower entry price (from $199/mo vs $249/mo), so the better value depends on which treatment you need.
RxSpan MD is a Beverly Hills telehealth practice founded by a plastic surgeon, offering compounded and branded GLP-1s, longevity peptides, hair-loss and ED treatment.
Visit RxSpan MD
Synergy Rx is a GLP-1 and peptide storefront launched in 2026 on CareValidate's white-label platform. It sells compounded semaglutide and tirzepatide as injections or oral tablets, prescribed through the Lion MD network.
Visit Synergy RxScore Breakdown
| Dimension | RxSpan MD | Synergy Rx |
|---|---|---|
| Overall Score | 59.1/100 ✓ | 51.9/100 |
| Trust & Safety30% | 60/100 ✓ | 48/100 |
| Value25% | 58/100 | 60/100 ✓ |
| Experience20% | 52/100 ✓ | 50/100 |
| Product Range15% | 78/100 ✓ | 58/100 |
| Reputation10% | 45/100 ✓ | 38/100 |
At a Glance
| Founded | 2026 | 2026 |
| Headquarters | Beverly Hills, CA | — |
| Publicly traded | No | No |
| Treatment categories | 4 | 3 |
| Treatments listed | 9 | 9 |
| Starting price | $249/mo | $199/mo |
Pricing Where They Compete
Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.
| Category | RxSpan MD | Synergy Rx |
|---|---|---|
| Weight Loss / GLP-1 | $249–$299 Compounded Semaglutide (injection or oral) | $199 Compounded Semaglutide (injectable) |
| Longevity & Peptides | $100–$200 Glutathione | $109 B12 Methylcobalamin |
| Sexual Health | $30–$100 ED (tadalafil, sildenafil/pycnogenol, vardenafil) | $275 PT-141 (bremelanotide) |
RxSpan MD
Synergy Rx
RxSpan MD vs Synergy Rx — FAQ
Is RxSpan MD better than Synergy Rx?
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RxSpan MD scores higher overall in our independent evaluation (59.1/100 vs 51.9/100), leading on trust & safety, experience, product range, reputation. Synergy Rx comes out ahead on value. Synergy Rx has the lower entry price (from $199/mo vs $249/mo), so the better value depends on which treatment you need.
Is RxSpan MD or Synergy Rx cheaper?
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Synergy Rx has the lower starting price (from $199/mo vs $249/mo for RxSpan MD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.
What do RxSpan MD and Synergy Rx both offer?
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Both platforms treat Weight Loss / GLP-1, Longevity & Peptides, Sexual Health. RxSpan MD covers 4 treatment categories total and Synergy Rx covers 3.
More Comparisons
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