Direct Meds vs RxSpan MD: Which Is Better?
Head-to-head comparison of Direct Meds and RxSpan MD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.
Our Verdict
Direct Meds scores higher overall in our independent evaluation (74.5/100 vs 59.1/100), leading on trust & safety, value, experience, reputation. RxSpan MD comes out ahead on product range.
Cash-pay telehealth brand selling compounded GLP-1s, HRT, longevity injectables and a rapid-dissolve ED tablet, filled by named partner pharmacies.
Visit Direct Meds
RxSpan MD is a Beverly Hills telehealth practice founded by a plastic surgeon, offering compounded and branded GLP-1s, longevity peptides, hair-loss and ED treatment.
Visit RxSpan MDScore Breakdown
| Dimension | Direct Meds | RxSpan MD |
|---|---|---|
| Overall Score | 74.5/100 ✓ | 59.1/100 |
| Trust & Safety30% | 72/100 ✓ | 60/100 |
| Value25% | 82/100 ✓ | 58/100 |
| Experience20% | 74/100 ✓ | 52/100 |
| Product Range15% | 72/100 | 78/100 ✓ |
| Reputation10% | 68/100 ✓ | 45/100 |
At a Glance
| Founded | 2021 | 2026 |
| Headquarters | Miami, FL | Beverly Hills, CA |
| Publicly traded | No | No |
| Treatment categories | 6 | 4 |
| Treatments listed | 9 | 9 |
| Starting price | $237/mo | $249/mo |
Pricing Where They Compete
Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.
| Category | Direct Meds | RxSpan MD |
|---|---|---|
| Weight Loss / GLP-1 | $237–$249 Compounded Semaglutide (sublingual) | $249–$299 Compounded Semaglutide (injection or oral) |
| Sexual Health | $53–$216 DirectMax rapid-dissolve ED tablet (apomorphine + sildenafil + tadalafil) | $30–$100 ED (tadalafil, sildenafil/pycnogenol, vardenafil) |
| Longevity & Peptides | $199–$299 NAD+ Injections | $100–$200 Glutathione |
Direct Meds
RxSpan MD
Direct Meds vs RxSpan MD — FAQ
Is Direct Meds better than RxSpan MD?
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Direct Meds scores higher overall in our independent evaluation (74.5/100 vs 59.1/100), leading on trust & safety, value, experience, reputation. RxSpan MD comes out ahead on product range.
Is Direct Meds or RxSpan MD cheaper?
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Direct Meds has the lower starting price (from $237/mo vs $249/mo for RxSpan MD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.
What do Direct Meds and RxSpan MD both offer?
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Both platforms treat Weight Loss / GLP-1, Sexual Health, Longevity & Peptides. Direct Meds covers 6 treatment categories total and RxSpan MD covers 4.
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