Direct Meds vs Sesame Care: Which Is Better?
Head-to-head comparison of Direct Meds and Sesame Care based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.
Our Verdict
Direct Meds scores higher overall in our independent evaluation (74.5/100 vs 74/100), leading on value, experience, product range. Sesame Care comes out ahead on trust & safety, reputation. Sesame Care has the lower entry price (from $149/mo vs $237/mo), so the better value depends on which treatment you need.
Cash-pay telehealth brand selling compounded GLP-1s, HRT, longevity injectables and a rapid-dissolve ED tablet, filled by named partner pharmacies.
Visit Direct Meds
Pay-per-visit marketplace connecting patients with licensed providers — no subscription needed for visits, with transparent per-visit pricing and optional memberships.
Visit Sesame CareScore Breakdown
| Dimension | Direct Meds | Sesame Care |
|---|---|---|
| Overall Score | 74.5/100 ✓ | 74/100 |
| Trust & Safety30% | 72/100 | 75/100 ✓ |
| Value25% | 82/100 ✓ | 80/100 |
| Experience20% | 74/100 ✓ | 70/100 |
| Product Range15% | 72/100 ✓ | 70/100 |
| Reputation10% | 68/100 | 70/100 ✓ |
At a Glance
| Founded | 2021 | 2019 |
| Headquarters | Miami, FL | New York, NY |
| Publicly traded | No | No |
| Treatment categories | 6 | 6 |
| Treatments listed | 9 | 7 |
| Starting price | $237/mo | $149/mo |
Pricing Where They Compete
Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.
| Category | Direct Meds | Sesame Care |
|---|---|---|
| Weight Loss / GLP-1 | $237–$249 Compounded Semaglutide (sublingual) | $59–$99 Weight Loss Program (subscription) |
| Men's Health | — | — |
| Women's Health | — | — |
Direct Meds
Sesame Care
Direct Meds vs Sesame Care — FAQ
Is Direct Meds better than Sesame Care?
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Direct Meds scores higher overall in our independent evaluation (74.5/100 vs 74/100), leading on value, experience, product range. Sesame Care comes out ahead on trust & safety, reputation. Sesame Care has the lower entry price (from $149/mo vs $237/mo), so the better value depends on which treatment you need.
Is Direct Meds or Sesame Care cheaper?
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Sesame Care has the lower starting price (from $149/mo vs $237/mo for Direct Meds). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.
What do Direct Meds and Sesame Care both offer?
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Both platforms treat Weight Loss / GLP-1, Men's Health, Women's Health. Direct Meds covers 6 treatment categories total and Sesame Care covers 6.
More Comparisons
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