Direct Meds vs Enhance.MD: Which Is Better?
Head-to-head comparison of Direct Meds and Enhance.MD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.
Our Verdict
Direct Meds scores higher overall in our independent evaluation (74.5/100 vs 66.9/100), leading on value, experience, product range, reputation. Enhance.MD comes out ahead on trust & safety. Enhance.MD has the lower entry price (from $169/mo vs $237/mo), so the better value depends on which treatment you need.
Cash-pay telehealth brand selling compounded GLP-1s, HRT, longevity injectables and a rapid-dissolve ED tablet, filled by named partner pharmacies.
Visit Direct Meds
Enhance.MD is a San Diego-based, physician-directed GLP-1 and NAD+ telehealth program that requires baseline and semiannual labs and video visits before and during treatment.
Visit Enhance.MDScore Breakdown
| Dimension | Direct Meds | Enhance.MD |
|---|---|---|
| Overall Score | 74.5/100 ✓ | 66.9/100 |
| Trust & Safety30% | 72/100 | 76/100 ✓ |
| Value25% | 82/100 ✓ | 60/100 |
| Experience20% | 74/100 ✓ | 68/100 |
| Product Range15% | 72/100 ✓ | 60/100 |
| Reputation10% | 68/100 ✓ | 65/100 |
At a Glance
| Founded | 2021 | 2019 |
| Headquarters | Miami, FL | San Diego, CA |
| Publicly traded | No | No |
| Treatment categories | 6 | 2 |
| Treatments listed | 9 | 5 |
| Starting price | $237/mo | $169/mo |
Pricing Where They Compete
Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.
| Category | Direct Meds | Enhance.MD |
|---|---|---|
| Weight Loss / GLP-1 | $237–$249 Compounded Semaglutide (sublingual) | $169 Microdose Tirzepatide |
| Longevity & Peptides | $199–$299 NAD+ Injections | $169 NAD+ Therapy |
Direct Meds
Enhance.MD
Direct Meds vs Enhance.MD — FAQ
Is Direct Meds better than Enhance.MD?
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Direct Meds scores higher overall in our independent evaluation (74.5/100 vs 66.9/100), leading on value, experience, product range, reputation. Enhance.MD comes out ahead on trust & safety. Enhance.MD has the lower entry price (from $169/mo vs $237/mo), so the better value depends on which treatment you need.
Is Direct Meds or Enhance.MD cheaper?
▾
Enhance.MD has the lower starting price (from $169/mo vs $237/mo for Direct Meds). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.
What do Direct Meds and Enhance.MD both offer?
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Both platforms treat Weight Loss / GLP-1, Longevity & Peptides. Direct Meds covers 6 treatment categories total and Enhance.MD covers 2.
More Comparisons
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