Defy Medical vs Josie: Which Is Better?
Head-to-head comparison of Defy Medical and Josie based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.
Our Verdict
Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 57.6/100), leading on trust & safety, experience, product range, reputation. Josie comes out ahead on value.
Physician-led telemedicine hormone clinic offering TRT, women's HRT, peptides, GLP-1s, and sexual-health treatments, dispensed through three named partner pharmacies.
Visit Defy Medical
Small menopause-focused telehealth brand selling compounded and branded GLP-1s, microdose GLP-1 maintenance plans and estradiol/progesterone HRT at flat published prices.
Visit JosieScore Breakdown
| Dimension | Defy Medical | Josie |
|---|---|---|
| Overall Score | 71.9/100 ✓ | 57.6/100 |
| Trust & Safety30% | 72/100 ✓ | 50/100 |
| Value25% | 60/100 | 70/100 ✓ |
| Experience20% | 78/100 ✓ | 58/100 |
| Product Range15% | 78/100 ✓ | 60/100 |
| Reputation10% | 80/100 ✓ | 45/100 |
At a Glance
| Founded | 2011 | — |
| Headquarters | Tampa, FL | — |
| Publicly traded | No | No |
| Treatment categories | 3 | 3 |
| Treatments listed | 4 | 7 |
| Starting price | $150/mo | $189/mo |
Pricing Where They Compete
Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.
| Category | Defy Medical | Josie |
|---|---|---|
| Hormone Therapy | $150–$250 Women's Bioidentical HRT | $90–$100 Estradiol Patch or Cream (HRT) |
| Weight Loss / GLP-1 | $150–$250 GLP-1 Weight Loss (Semaglutide/Tirzepatide) | $189 Microdose GLP-1 Maintenance (semaglutide or tirzepatide) |
Defy Medical
Josie
Defy Medical vs Josie — FAQ
Is Defy Medical better than Josie?
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Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 57.6/100), leading on trust & safety, experience, product range, reputation. Josie comes out ahead on value.
Is Defy Medical or Josie cheaper?
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Defy Medical has the lower starting price (from $150/mo vs $189/mo for Josie). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.
What do Defy Medical and Josie both offer?
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Both platforms treat Hormone Therapy, Weight Loss / GLP-1. Defy Medical covers 3 treatment categories total and Josie covers 3.
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