5 Best Rapamycin Providers of November 2026
Quick answer
As of November 2026, our top-rated place to get Rapamycin online is AgelessRx (7.8/10, from $65/mo), followed by Healthspan (from $64/mo) and AlgoRx (from $114/mo). Across the 5 providers we compared, starting prices run $64–$114/mo (median $99).
- Our #1 pick1
AgelessRx- From $65/mo for Rapamycin (sirolimus)
- Price includes provider visits and shipping
- Deepest longevity formulary we track: rapamycin ($65/mo), metformin and LDN ($25/mo), NAD+, sermorelin…
7.8Very Good - 2
Healthspan- From $64/mo for The Rapamycin Protocol
- Price includes provider visits, lab work and shipping
- Deepest rapamycin-centered longevity formulary we track: oral and topical rapamycin, SGLT2 inhibitors…
7.3Good - 3
AlgoRx- From $114/mo for Rapamycin
- Offer: $99 + $15 provider fee; $15 shipping under $250
- One of the widest men's menus tracked: 59 products including enclomiphene, anastrozole, cabergoline…
6.7Good - 4
Fella HealthNo Price Jump After Month 1Same Price at Every Dose- From $99/mo for Rapamycin
- Price includes provider visits and shipping
- Covers men's hormone and longevity needs alongside weight loss: enclomiphene from $99–149/mo, oral TRT…
6.7Good - 5
HeallyNames Its Pharmacy- From $99/mo for Rapamycin
- Price includes provider visits and shipping
- Broad longevity menu: rapamycin, NAD+, sermorelin, glutathione, methylene blue and metformin
6.6Good
Side-by-side comparison
| # | Provider | Score | From | Intro offer | Labs |
|---|---|---|---|---|---|
| 1 | AgelessRx | 7.8 | $65/mo | — | — |
| 2 | Healthspan | 7.3 | $64/mo | — | Included |
| 3 | AlgoRx | 6.7 | $114/mo | Yes | — |
| 4 | Fella Health | 6.7 | $99/mo | — | — |
| 5 | Heally | 6.6 | $99/mo | — | — |
Starting prices as listed on each provider's site, checked Nov 4, 2026. Prices can change with dose, plan length and promotions.
Key numbers
- 5 providers compared
- Lowest starting price: $64/mo
- Median starting price: $99/mo
- 1 of 5 include lab work in at least one plan
- 1 of 5 have an intro offer or first-month discount
How we ranked these
Ranked by our category score: trust and safety (30%), value (25%), patient experience (20%), product range in this category (15%) and reputation (10%). Scores come from our own research into each provider's website, regulatory records, patient reviews and pricing. Read the full methodology
What to look for
What rapamycin is
Rapamycin (sirolimus) is an FDA-approved immunosuppressant used to prevent kidney transplant rejection and to treat lymphangioleiomyomatosis (LAM). It is the most consistently effective lifespan-extending drug in mouse studies, which has made low-dose, intermittent rapamycin one of the most common off-label longevity prescriptions. Human evidence for longevity benefit is early and unproven.
How it works
Rapamycin inhibits mTOR (mechanistic target of rapamycin), a central nutrient-sensing pathway that drives cell growth. Dampening mTOR activity mimics some effects of calorie restriction and activates autophagy, the cell's recycling process. In the NIA Interventions Testing Program, rapamycin extended median and maximum lifespan in mice, even when started late in life. In humans, a small study of a related mTOR inhibitor improved vaccine response in older adults, and the 2025 PEARL trial found low-dose intermittent rapamycin reasonably well tolerated over 48 weeks with modest, mixed effects on secondary measures. No trial has shown it extends human lifespan or healthspan.
What to expect
Longevity protocols typically use low doses once weekly (commonly 3–6 mg) rather than the daily dosing used in transplant medicine, to limit immunosuppression and metabolic side effects. There is no established timeline for measurable benefit; monitoring labs are usually repeated after the first few months.
Who it's not for
People with active or recurrent infections; People with upcoming surgery or unhealed wounds; Pregnant or breastfeeding women, or those trying to conceive; People taking strong CYP3A4 inhibitors or other immunosuppressants without specialist oversight; People with poorly controlled diabetes or severe hyperlipidemia.
Frequently asked questions
Where is the best place to get Rapamycin online?
▾
AgelessRx ranks #1 on this list with a score of 7.8/10 and plans from $65/mo. Scores weigh trust and safety, value, patient experience, product range and reputation.
What is the cheapest way to get Rapamycin online?
▾
Of the providers on this list, Healthspan has the lowest starting price at $64/mo (The Rapamycin Protocol). Starting prices often rise with dose or after an intro period, so compare the ongoing price too.
How much does Rapamycin cost online?
▾
Across the 5 providers we compared, starting prices range from $64 to $114 per month, with a median of $99. 1 of them run an intro offer or first-month discount.
How are these providers ranked?
▾
By our category score: trust and safety (30%), value (25%), patient experience (20%), product range in this category (15%) and reputation (10%), with a small bonus for specialists. The full methodology is published on our methodology page.
Is rapamycin approved for longevity?
▾
No. Sirolimus is FDA-approved for transplant rejection prevention and LAM. Prescribing it for aging is off-label — legal for a licensed clinician, but based on animal data and early human studies rather than proof of benefit in people.
Is low-dose rapamycin safe?
▾
Small human studies suggest intermittent low doses are generally tolerated, with mouth sores and lipid or glucose changes the most common issues. It is still an immunosuppressant, so infection risk, surgery timing, and drug interactions all need attention. Monitoring labs are part of responsible prescribing.
How much does rapamycin cost through telehealth?
▾
Generic sirolimus itself is inexpensive at low weekly doses — often roughly $20–80 per month. Most of the cost of a longevity program is the membership, consults, and labs, putting typical all-in pricing around $50–200 per month.
What about metformin for longevity?
▾
Metformin is another off-label longevity prescription with supportive observational and animal data. The TAME trial was designed to test whether it delays age-related disease in humans, but results are not available. As with rapamycin, it should be treated as a hypothesis, not an established anti-aging treatment.